VetGen - Veterinary Genetic Services

We screen our dogs through the Orthopedic Foundation for Animals. Hip dysplasia is a polygenic disorder: groups of genes contribute to this problem, not just one particular gene. With consistent testing of both parents, grandparents, etc. this abnormality can be managed.

Inside Edition reported this week on the availability of genetic testing for dogs

Testing for the Exercise Induced Collapse (EIC) gene can be performed on blood, cheek swabs, dew claws and semen. The results are useful for owners in making decisions about the activities their dog can and cannot participate in, for breeders to assist them in making breeding decisions and for veterinarians as they are diagnosing dogs with possible neurological, neuromuscular or metabolic disorders.

Animal DNA testing services for canine, equine, dog, & horse

May 18, 2017 - This page is used to search for Genetic Testing Laboratories and their corresponding tests for hereditary diseases in dogs and cats The method of genetic transmission of deafness in dogs is usually not known. There are no recognized forms of sex-linked deafness in dogs, although this does occur in humans. The disorder has been reported to have an autosomal recessive mechanism in the Rottweiler, Bull Terrier, and Pointer, but this suggestion is not reliable because the reports were before the availability of BAER testing and the ability to detect unilaterally deaf dogs. References usually state that deafness transmission in most other breeds is autosomal dominant, but this is false, as will be discussed below. Pigment-associated inherited deafness is not restricted to dogs. Similar defects have been reported for mice, mink, pigs, horses, cattle, cats, and humans. Deafness in blue-eyed white cats is common and is known to be passed on as an autosomal dominant defect. Blue eyes, resulting from an absence of pigment in the iris, is common with pigment-associated deafness but is not, in and of itself, an indication of deafness or the presence of a deafness gene; however, in several breeds dogs (Dalmatian, English Setter, English Cocker Spaniel, Bull Terrier) with blue eyes are statistically more likely to be deaf. Waardenburg's syndrome, a human condition, presents with deafness, a stripe of white in the hair and beard, blue or different colored eyes (even in blacks and asians), no pigment behind the retina, and minor structural deformities around the nose and eyes. This is an autosomal dominant disorder with incomplete penetrance, which means that individuals that inherit the disorder may not show all components of the syndrome - i.e., they may not be deaf. Incomplete penetrance of a defect greatly complicates the determination of mode of inheritance. At present there is no documentation that incomplete penetrance is a factor in any canine deafness.

Embark Dog DNA Test - Breed, Health and More

The prevalence of congenital deafness in different breeds is seldom known because of the limited number of studies (see table on ). In the Dalmatian, where the incidence is highest, 8% of all dogs in the US are bilaterally deaf and 22% are unilaterally deaf. In the English Setter, English Cocker Spaniel, Australian Cattle Dog, and Bull Terrier, where fewer numbers of dogs have been hearing tested, the incidence appears to be about one third to one half that of Dalmatians. Unilateral or bilateral deafness is found in 75% of all white Norwegian Dunkerhounds, but the incidence in normal-color dogs is unknown. Other breeds with a high incidence are the Catahoula and Australian Shepherd. The incidence of all types of deafness in the general dog population is low, reported to be 2.56 to 6.5 cases per 10,000 dogs seen at veterinary school teaching hospitals, but these data predate the availability of hearing testing devices and so are much lower that actual values. Recognition of affected cases is often difficult, because unilaterally deaf dogs appear to hear normally unless a special test (the brainstem auditory evoked response, BAER) is performed; facilities to perform the BAER are usually only available at veterinary schools (see list of ). It should be noted that a unilaterally deaf dog can be as great a genetic risk for transmission of deafness to its offspring as is a bilaterally deaf dog.

Dog Tests - UC Davis Veterinary Genetics Laboratory